A common feature of Alzheimer’s Disease (AD), Parkinson’s Disease (PD) and Amylotrophic Lateral Sclerosis (ALS), is the accumulation of insoluble protein aggregates (mis-folded proteins). AD involves β-amyloid, PD involves α-synuclein and ALS involves SOD1. Experimental evidence shows that the generation of free radicals (reactive oxygen species, superoxides) from the mitochondria are the primary driving force for the formation of these insoluble protein aggregates, and are a major factor in the initiation and progression of these debilitating neurodegenerative diseases.

Anti-oxidants have been employed to combat free radicals after their formation. Also redox sensitive molecules have been used to trap the free radicals and feed them back into the electron transport chain. Attempts to absorb, scavenge or redirect free radicals have met with little success. Our approach is very different: PREVENT the initial formation of free radicals.

” An ounce of prevention is worth a pound of cure”, Benjamin Franklin.